Prevalence and Clinical Impact of Donor-Specific Alloantibody Among Intestinal Transplant Recipients
نویسندگان
چکیده
منابع مشابه
Effect of donor-specific antibodies and panel reactive antibodies in living donor liver transplant recipients
PURPOSE Preformed circulating donor-specific antibodies (DSAs) immunologically challenge vascular endothelium and the bile duct. However, the liver is an immune-tolerant organ and can avoid immunological challenges. This study was undertaken to analyze the effects of DSAs after adult living donor liver transplantation (LDLT). METHODS We retrospectively reviewed 219 LDLT patients' records trea...
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Tacrolimus, a cornerstone of immunosuppressive therapy in solid organ transplantation, has a narrow therapeutic range with considerable inter-individual and intra-individual pharmacokinetic variability. To date, there is no information on the pharmacokinetics of tacrolimus in Iranian liver transplant recipients. This study was designed to determine pharmacokinetic properties of orally administe...
متن کاملClinical Pharmacokinetics of Tacrolimus in Iranian Liver Transplant Recipients
Tacrolimus, a cornerstone of immunosuppressive therapy in solid organ transplantation, has a narrow therapeutic range with considerable inter-individual and intra-individual pharmacokinetic variability. To date, there is no information on the pharmacokinetics of tacrolimus in Iranian liver transplant recipients. This study was designed to determine pharmacokinetic properties of orally administe...
متن کاملIncidence and impact of de novo donor-specific alloantibody in primary renal allografts.
BACKGROUND To date, limited information is available describing the incidence and impact of de novo donor-specific anti-human leukocyte antigen (HLA) antibodies (dnDSA) in the primary renal transplant patient. This report details the dnDSA incidence and actual 3-year post-dnDSA graft outcomes. METHODS The study includes 189 consecutive nonsensitized, non-HLA-identical patients who received a ...
متن کاملPost-Transplant Glomerulonephritis in Live-Donor Renal Transplant Recipients: Clinical Course and Risk Factors
Kidney transplantation is the treatment of choice for end-stage renal disease. It offers better quality of life and minimizes the mortality risk for patients when compared with maintenance dialysis therapy (Chailimpamontree W, et al., 2009). Little data are available concerning the impact of the post-transplantation glomerulonephritis (GN) on graft outcome (Gaston R, 2006). The post-transplant ...
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ژورنال
عنوان ژورنال: Transplantation
سال: 2017
ISSN: 0041-1337
DOI: 10.1097/tp.0000000000001391